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KMID : 0381919730030010039
Korean Journal of Microscopy
1973 Volume.3 No. 1 p.39 ~ p.44
Electron Microscopic Studies on the Rat Mast Cells Induced by Morphine Hydrochloride


Abstract
The effects of morphine HCI on the mesenteric mast cells were studied the electron microscopy.
The results of the observations are as follows
1. In the experimental group for intravenous injection of morphine HCl. 12 mg/kg, the granules appeared cluster, granular lysis and an electron transparent appearance. Frequently, some granules appeared in the extra cellular space.
2. In the experimental group for intravenous injection of morphine HCl 24 mg/ kg, it was observed that the formation of a clear halo or a space around each granule. Many altered granules showing -a -reticular-texture (type 2 are observed in the cytoplasm.
3. From the results mentioned above, it is suggested that rat mesenteric mast cell granules were affected by morphine HCl.
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